|introduction||Ornithine alpha-ketoglutarate (OKG) is manufactured from two amino acids, ornithine and glutamine. These amino acids are called “conditionally essential.” This means that ordinarily one does not need to consume them in food because the body can manufacture them from other nutrients. However, during periods of severe stress, such as recovery from major trauma or severe illness, the body may not be able to manufacture them in sufficient quantities, and may require an external source.|
|Indications and Uses|| OKG may play a role in the treatment of individuals recovering from severe physical trauma. |
When the body experiences severe trauma—such as injury, major surgery , or burns—it goes into what is called a catabolic state. In this temporary condition, the body tends to tear itself down rather than build itself up. The catabolic hormone cortisone plays a major role in inducing catabolism. In the catabolic state, the body fails to utilize protein found in the diet, and high levels of protein breakdown products appear in the urine. Calcium levels in urine also rise, as bones begin to weaken.
|The Information had not been evaluated by the Food and Drug Administration, only for reference|